SCHEMBL11234764

SCHEMBL11234764

O=C(O)[C@]1(Cc2ccc(F)cc2)CCCN1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.56
SLC6A2 P23975 4/20 0.45
SLC6A4 P31645 4/20 0.45
SLC6A3 Q01959 4/20 0.45
ARG1 P05089 1/20 0.43
ARG2 P78540 1/20 0.43
PARP1 P09874 4/20 0.43
HSD11B1 P28845 2/20 0.39
CYP2D6 P10635 3/20 0.38
KCNH2 Q12809 2/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1819135 1.00 HRH3 (0.56) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL440476 0.87 SLC6A2 (0.56) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL414249 0.87 SLC6A2 (0.56) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL10956783 0.87 SLC6A2 (0.56) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL1816048 0.86 SLC6A2 (0.44) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL1817184 0.86 SLC6A2 (0.44) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL4849081 0.86 SLC6A2 (0.44) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL29352273 0.86 SLC6A2 (0.44) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL11242292 0.86 SLC6A2 (0.44) HRH3SLC6A2SLC6A4SLC6A3ARG1
SCHEMBL1818182 0.86 SLC6A2 (0.44) HRH3SLC6A2SLC6A4SLC6A3ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055379-A Compounds containing one or more diboronate esters and related insulin analogues 普罗托莫科技公司 2026-05-15 CN disclosed
CN-119677541-A Aromatic boron-containing compounds and related insulin analogues 原聚体科技公司 2025-03-21 CN disclosed
CN-113967258-B FAP-activated therapeutic agents and related uses 塔夫茨大学信托人 2024-07-02 CN disclosed
CN-116917297-A Aromatic boron-containing compounds and insulin analogues 原聚体科技公司 2023-10-20 CN disclosed
US-20230134116-A1 CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS PROTOMER TECHNOLOGIES, INC. 2023-05-04 US disclosed
CN-115843257-A Conjugates for selective responsiveness to vicinal diols 原聚体科技公司 2023-03-24 CN disclosed
EP-4126058-A1 CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS Protomer Technologies Inc. (US) 2023-02-08 EP disclosed
WO-2021202802-A1 CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS PROTOMER TECHNOLOGIES INC. (US) 2021-10-07 WO disclosed
WO-2021081110-A2 PEPTIDES AND USE THEREOF ANEXIGEN, INC. (US) 2021-04-29 WO disclosed
US-4316905-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134116-A1 CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS GPR119, GLP1R, IAPP HRH3 1847/4885SLC6A2 548/4885SLC6A4 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.