SCHEMBL440476

SCHEMBL440476

O=C(O)C1(Cc2ccccc2)CCCN1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 7/20 0.56
SLC6A4 P31645 7/20 0.56
SLC6A3 Q01959 7/20 0.56
HRH3 Q9Y5N1 4/20 0.54
ARG1 P05089 1/20 0.45
ARG2 P78540 1/20 0.45
PARP1 P09874 1/20 0.41
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CYP2D6 P10635 4/20 0.38
KCNH2 Q12809 2/20 0.38
AKR1C1 Q04828 1/20 0.37
ALDH1A1 P00352 1/20 0.37
ADRB2 P07550 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL414249 1.00 SLC6A2 (0.56) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL10956783 1.00 SLC6A2 (0.56) SLC6A2SLC6A4SLC6A3HRH3ARG1
Hydrochloric Acid SCHEMBL7375378 0.98 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL7455945 0.95 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL8083651 0.95 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL1819249 0.91 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL1052527 0.87 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL14828670 0.87 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL1052525 0.87 SLC6A2 (0.54) SLC6A2SLC6A4SLC6A3HRH3ARG1
SCHEMBL11234764 0.87 HRH3 (0.56) SLC6A2SLC6A4SLC6A3HRH3ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3914068-A1 COMPOSITIONS FOR TREATING CITRUS DISEASE AND PROMOTING YIELD INCREASE IN ROW CROPS Spogen Biotech Inc. (US) 2021-12-01 EP claimed
WO-2020154387-A1 COMPOSITIONS FOR TREATING CITRUS DISEASE AND PROMOTING YIELD INCREASE IN ROW CROPS SPOGEN BIOTECH INC. (US) 2020-07-30 WO claimed
CN-109219592-A Benzyl phenylate analog derivative and its preparation method and pharmaceutical composition and purposes 中国医学科学院药物研究所 2019-01-15 CN claimed
CN-108148113-A A kind of solid phase synthesis process of nmda receptor adjusting control agent tetrapeptide derivative 深圳先进技术研究院 2018-06-12 CN claimed
CN-107417572-A Benzyl phenylate analog derivative and its preparation method and pharmaceutical composition and purposes 中国医学科学院药物研究所 2017-12-01 CN claimed
US-20150353619-A1 Non-Canonical Insulins and Their Uses CALIFORNIA INSTITUTE OF TECHNOLOGY 2015-12-10 US claimed
US-20260116855-A1 ORALLY ACTIVE MELANOCORTIN RECEPTOR-4 COMPOUNDS PALATIN TECHNOLOGIES INC (US) 2026-04-30 US disclosed
EP-4696334-A2 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2026-02-18 EP disclosed
EP-4694932-A2 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS Protomer Technologies Inc. (US) 2026-02-18 EP disclosed
US-12514938-B2 Fibroblast activation protein targeting peptides PERSPECTIVE THERAPEUTICS, INC. (US) 2026-01-06 US disclosed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP disclosed
US-20250249074-A1 GLUCOSE RESPONSIVE INSULINS PROTOMER TECHNOLOGIES INC. 2025-08-07 US disclosed
WO-2025128149-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-19 WO disclosed
EP-1554274-A1 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS GLAXO GROUP LIMITED (GB) 2005-07-20 EP disclosed
WO-2005023815-A2 NEUROPROTECTIVE BICYCLIC COMPOUNDS AND METHODS FOR THEIR USE NEUREN PHARMACEUTICALS LIMITED (NZ) 2005-03-17 WO disclosed
WO-2004037818-A1 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS GLAXO GROUP LIMITED (GB) 2004-05-06 WO disclosed
US-4499287-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1985-02-12 US disclosed
US-4456761-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1984-06-26 US disclosed
US-4356182-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-10-26 US disclosed
US-4291040-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1981-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250249074-A1 GLUCOSE RESPONSIVE INSULINS GLP1R, GPR119, IAPP SLC6A2 2940/4885SLC6A4 3233/4885SLC6A3 3023/4885
US-20150353619-A1 Non-Canonical Insulins and Their Uses IAPP, IDE, INSR SLC6A2 2907/4885SLC6A4 2324/4885SLC6A3 3157/4885
US-20260116855-A1 ORALLY ACTIVE MELANOCORTIN RECEPTOR-4 COMPOUNDS MC1R, MC3R, MC5R SLC6A2 155/4885SLC6A4 137/4885SLC6A3 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.