SCHEMBL414267

SCHEMBL414267

O=Cc1cc(Br)ccc1Br

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.61
CYP2A6 P11509 3/20 0.47
HSP90AA1 P07900 1/20 0.46
TLR9 Q9NR96 1/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.46
PRKDC P78527 1/20 0.43
ALDH1A1 P00352 1/20 0.43
PTPN1 P18031 1/20 0.43
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
S100A4 P26447 1/20 0.41
LMNA P02545 2/20 0.39
PIM3 Q86V86 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MEN1 O00255 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3040456 0.82 ERN1 (0.64) ERN1CYP2A6HSP90AA1TLR9PTGDR2
SCHEMBL203395 0.80 ERN1 (0.61) ERN1CYP2A6PTGDR2ALDH1A1PTPN1
SCHEMBL1162125 0.80 ERN1 (0.56) ERN1CYP2A6HSP90AA1TLR9PTGDR2
SCHEMBL16765589 0.78 ERN1 (0.59) ERN1CYP2A6HSP90AA1TLR9PTGDR2
SCHEMBL29447322 0.78 ALDH1A3 (0.48) ERN1CYP2A6PRKDCALDH1A1LMNA
SCHEMBL16247118 0.78 ALDH1A3 (0.48) ERN1CYP2A6PRKDCALDH1A1LMNA
5-Bromosalicylaldehyde SCHEMBL79219 0.76 ERN1 (1.00) ERN1PTGDR2CA12CA9LMNA
SCHEMBL380473 0.76 ERN1 (0.57) ERN1PRKDCALDH1A1PTPN1S100A4
SCHEMBL144351 0.76 ERN1 (0.57) ERN1CYP2A6PTGDR2PRKDCALDH1A1
SCHEMBL18699 0.76 ERN1 (0.57) ERN1CYP2A6PTGDR2ALDH1A1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-114920907-B Aminated porous aromatic skeleton compound and preparation method and application thereof 福建农林大学 2023-06-20 CN claimed
CN-114920907-A Aminated porous aromatic skeleton compound and preparation method and application thereof 福建农林大学 2022-08-19 CN claimed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN claimed
US-20210115310-A1 ADHESION-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL PORCHER INDUSTRIES (FR) 2021-04-22 US claimed
EP-3784719-A1 ADHERENCE-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL Porcher Industries (FR) 2021-03-03 EP claimed
CN-112135862-A Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2020-12-25 CN claimed
CN-102558184-B Synthesis method of phthalazine derivative UNIV SOUTHWEST 2014-07-16 CN claimed
EP-4680612-A1 CHEMICAL COMPOUNDS AN2 Therapeutics, Inc. (US) 2026-01-21 EP disclosed
EP-4665730-A1 HETEROCYCLIC GLP-1 AGONISTS Gasherbrum Bio, Inc. (US) 2025-12-24 EP disclosed
US-12291529-B2 Heterocyclic GLP-1 agonists GASHERBRUM BIO, INC. (US) 2025-05-06 US disclosed
WO-2025060786-A1 SIX-MEMBERED AND FIVE-MEMBERED FUSED RING DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湘北威尔曼制药股份有限公司 2025-03-27 WO disclosed
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US disclosed
EP-0247320-B1 5-ARYLALKYL-4-ALKOXY-2(5H)-FURANONES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION AS WELL AS THEIR APPLICATION AS THERAPEUTICALLY ACTIVE INGREDIENTS SCHWABE WILLMAR GMBH & CO (DE) 1990-12-27 EP disclosed
EP-0328669-A1 CHALCONE DERIVATIVE COMPOUNDS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed
US-4855320-A ANTICONVULSANTS, ANTIEPILEPTICS DR. WILLMAR SCHWABE GMBH & COMPANY (DE) 1989-08-08 US disclosed
EP-0247320-A2 5-Arylalkyl-4-alkoxy-2(5H)-furanones, intermediates and process for their preparation as well as their application as therapeutically active ingredients Dr. Willmar Schwabe GmbH & Co. (DE) 1987-12-02 EP disclosed
US-4450298-A Vapor phase catalytic hydrolysis of benzal chloride or its halogen- or trifluoromethyl-substitute to form benzaldehyde or substitute CENTRAL GLASS COMPANY, LIMITED (JP) 1984-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12291529-B2 Heterocyclic GLP-1 agonists GLP1R, GIPR, IAPP ERN1 2702/4885CYP2A6 2860/4885HSP90AA1 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.