Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16050049 | 0.86 | ERN1 (0.48) | ERN1CYP2A6S100A4PTGDR2ALDH1A1 | |
| SCHEMBL1985834 | 0.83 | ERN1 (0.50) | ERN1CYP2A6S100A4PTGDR2ALDH1A1 | |
| SCHEMBL17426244 | 0.83 | ERN1 (0.56) | ERN1PTGDR2ALDH1A1LMNATDP1 | |
| SCHEMBL405754 | 0.83 | ALDH1A1 (0.47) | ERN1CYP2A6S100A4PTGDR2ALDH1A1 | |
| SCHEMBL3040456 | 0.82 | ERN1 (0.64) | ERN1CYP2A6PTGDR2ALDH1A1PTPN1 | |
| SCHEMBL26647840 | 0.80 | XDH (0.49) | ERN1CYP2A6S100A4PTGDR2MCL1 | |
| SCHEMBL414267 | 0.80 | ERN1 (0.61) | ERN1CYP2A6S100A4PTGDR2ALDH1A1 | |
| SCHEMBL16765589 | 0.78 | ERN1 (0.59) | ERN1CYP2A6S100A4PTGDR2ALDH1A1 | |
| SCHEMBL23861136 | 0.78 | ERN1 (0.49) | ERN1S100A4ALDH1A1MEN1LMNA | |
| SCHEMBL28032764 | 0.78 | ERN1 (0.44) | ERN1CYP2A6S100A4PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626716-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2020-03-25 | — | — | EP | disclosed |
| US-9981955-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2018-05-29 | — | — | US | disclosed |
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-02-02 | — | — | US | disclosed |
| US-9511056-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2016-12-06 | — | — | US | disclosed |
| CN-103977406-B | Antiviral compound | 吉利德制药有限责任公司 | 2016-10-19 | — | — | CN | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |
| US-20160013429-A1 | ORGANIC THIN FILM TRANSISTOR | FUJIFILM CORPORATION (JP) | 2016-01-14 | — | — | US | disclosed |
| CN-104230900-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-12-24 | — | — | CN | disclosed |
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| US-8088368-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-1717258-B1 | DIHALIDE, POLYMER COMPOUND AND METHOD FOR PRODUCING SAME | TOKYO INST TECH (JP) | 2011-10-19 | — | — | EP | disclosed |
| US-20100310512-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2010-12-09 | — | — | US | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| US-7462683-B2 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462683-B2 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2008-12-09 | — | — | US | disclosed |
| US-20070185306-A1 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070185306-A1 | Dihalide, polymer compound and method for producing the same | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1717258-A1 | DIHALIDE, POLYMER COMPOUND AND METHOD FOR PRODUCING SAME | Tokyo Institute of Technology (JP) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185306-A1 | Dihalide, polymer compound and method for producing the same | HSPA4L, HDHD5, MRPL21 | ERN1 1646/4885CYP2A6 926/4885S100A4 2960/4885 |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | ERN1 147/4885CYP2A6 2659/4885S100A4 2797/4885 |
| US-20160013429-A1 | ORGANIC THIN FILM TRANSISTOR | SCN8A, SLC8A1, NTRK1 | ERN1 3099/4885CYP2A6 3398/4885S100A4 718/4885 |
| US-20100310512-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | ERN1 147/4885CYP2A6 2659/4885S100A4 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.