Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28441606 | 1.00 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2TSHRTP53 | |
| SCHEMBL14920263 | 0.97 | HCAR2 (0.36) | HCAR2KEAP1NFE2L2TSHRTP53 | |
| SCHEMBL21541926 | 0.79 | HCAR2 (0.55) | HCAR2KEAP1NFE2L2TSHRTP53 | |
| SCHEMBL2351118 | 0.79 | HCAR2 (0.55) | HCAR2KEAP1NFE2L2TSHRTP53 | |
| SCHEMBL29212697 | 0.77 | LMNA (0.40) | TSHRTP53ALDH1A1 | |
| SCHEMBL2036721 | 0.75 | LDHA (0.33) | TSHRALDH1A1 | |
| SCHEMBL30211149 | 0.75 | LMNA (0.38) | TSHRTP53ALDH1A1 | |
| SCHEMBL4838653 | 0.73 | HCAR2 (0.42) | HCAR2KEAP1NFE2L2TSHRTP53 | |
| SCHEMBL7568618 | 0.73 | HCAR2 (0.42) | HCAR2KEAP1NFE2L2TSHRTP53 | |
| SCHEMBL8629325 | 0.72 | LDHA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090050245-A1 | DECOY COUNTERMEASURES | CHEMRING COUNTERMEASURES LIMITED (GB) | 2009-02-26 | — | — | US | claimed |