Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.53 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | OSBP | P22059 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.49 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.46 |
| ▸ | ST3GAL1 | Q11201 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | UGCG | Q16739 | 2/20 | 0.46 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430017 | 0.89 | CYP46A1 (0.54) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL30475052 | 0.89 | CYP46A1 (0.54) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL8608988 | 0.83 | POLA1 (0.75) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL28273010 | 0.83 | POLA1 (0.75) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL11497304 | 0.83 | POLA1 (0.75) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL8839992 | 0.83 | POLA1 (0.75) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL28088865 | 0.83 | POLA1 (0.75) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL29356325 | 0.83 | POLA1 (0.73) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL28404863 | 0.83 | POLA1 (0.73) | POLA1CYP46A1NPC1L1NPC1PLA2G2A | |
| SCHEMBL8425524 | 0.83 | POLA1 (0.73) | POLA1CYP46A1NPC1L1NPC1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8454991-B2 | Method and device for photodynamic therapy | QUEST PHARMATECH INC. | 2013-06-04 | — | — | US | claimed |
| US-20090204057-A1 | METHOD AND DEVICE FOR PHOTODYNAMIC THERAPY | QUEST PHARMATECH INC. (CA) | 2009-08-13 | — | — | US | claimed |
| WO-2008011707-A1 | METHOD AND DEVICE FOR PHOTODYNAMIC THERAPY | QUEST PHARMATECH INC. (CA) | 2008-01-31 | — | — | WO | claimed |
| EP-1039834-B1 | OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE | IMARX PHARMACEUTICAL CORP (US) | 2005-09-28 | — | — | EP | claimed |
| EP-1039834-A4 | OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE | IMARX PHARMACEUTICAL CORP (US) | 2001-12-05 | — | — | EP | claimed |
| EP-1039834-A1 | OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE | IMARX PHARMACEUTICAL CORP. (US) | 2000-10-04 | — | — | EP | claimed |
| US-6123923-A | ADMINISTERING A PATIENT A CONTRAST AGENT CONTAINING A STABILIZER, A PHOTOACTIVE AGENT, A GASEOUS PRECURSOR SUCH AS PERFLUORINATED COMPOUND OR GAS OR BOTH, AND SCANNING THE PATIENT USING ULTRASOUND IMAGING AND OPTICAL IMAGING | IMARX PHARMACEUTICAL CORP. (US) | 2000-09-26 | — | — | US | claimed |
| WO-1999030620-A1 | OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE | IMARX PHARMACEUTICAL CORP. (US) | 1999-06-24 | — | — | WO | claimed |
| US-8454991-B2 | Method and device for photodynamic therapy | QUEST PHARMATECH INC. | 2013-06-04 | — | — | US | disclosed |
| US-20090204057-A1 | METHOD AND DEVICE FOR PHOTODYNAMIC THERAPY | QUEST PHARMATECH INC. (CA) | 2009-08-13 | — | — | US | disclosed |
| EP-1651276-A4 | EMULSION PARTICLES FOR IMAGING AND THERAPY AND METHODS OF USE THEREOF | BARNES JEWISH HOSPITAL (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-2019667-A2 | DETECTION AND IMAGING OF TARGET TISSUE | Barnes-Jewish Hospital (US) | 2009-02-04 | — | — | EP | disclosed |
| EP-1684724-A4 | ENHANCED DRUG DELIVERY | BARNES JEWISH HOSPITAL (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2008011707-A1 | METHOD AND DEVICE FOR PHOTODYNAMIC THERAPY | QUEST PHARMATECH INC. (CA) | 2008-01-31 | — | — | WO | disclosed |
| WO-2005014051-A1 | EMULSION PARTICLES FOR IMAGING AND THERAPY AND METHODS OF USE THEREOF | BARNES-JEWISH HOSPITAL (US) | 2005-02-17 | — | — | WO | disclosed |
| US-20020102216-A1 | Enhanced ultrasound detection with temperature-dependent contrast agents | KEREOS, INC. | 2002-08-01 | — | — | US | disclosed |
| EP-1039834-A4 | OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE | IMARX PHARMACEUTICAL CORP (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-1039834-A1 | OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE | IMARX PHARMACEUTICAL CORP. (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6123923-A | ADMINISTERING A PATIENT A CONTRAST AGENT CONTAINING A STABILIZER, A PHOTOACTIVE AGENT, A GASEOUS PRECURSOR SUCH AS PERFLUORINATED COMPOUND OR GAS OR BOTH, AND SCANNING THE PATIENT USING ULTRASOUND IMAGING AND OPTICAL IMAGING | IMARX PHARMACEUTICAL CORP. (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999030620-A1 | OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE | IMARX PHARMACEUTICAL CORP. (US) | 1999-06-24 | — | — | WO | disclosed |