SCHEMBL4142896

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4008572	0.83	L3MBTL1 (0.54)	HTR6TNFSF11NAMPTTNFTSHR
	SCHEMBL4004754	0.82	HTR6 (0.50)	HTR6TNFSF11DRD2KLK7
	SCHEMBL1413325	0.79	HTR6 (0.58)	HTR6DRD2KLK7
	SCHEMBL5411264	0.79	HTR6 (0.56)	HTR6DRD2
	SCHEMBL1413680	0.79	HTR6 (0.50)	HTR6TNFSF11NAMPTDRD2
	SCHEMBL1413480	0.78	HTR6 (0.52)	HTR6TNFSF11DRD2
	SCHEMBL1413462	0.77	HTR6 (0.66)	HTR6DRD2KLK7
	SCHEMBL1413801	0.77	HTR6 (0.50)	HTR6TNFSF11NAMPTDRD2
	SCHEMBL1413799	0.77	HTR6 (0.50)	HTR6TNFSF11NAMPTDRD2
	SCHEMBL1413595	0.76	HTR6 (0.50)	HTR6NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.