Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 5/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186313 | 0.88 | ALDH1A1 (0.50) | HTTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL28811140 | 0.85 | KDM4E (0.53) | HTTCYP2C9HSD17B10HRH3ALDH1A1 | |
| SCHEMBL7329753 | 0.83 | KDM4E (0.55) | HTTCYP2C9HSD17B10HRH3ALDH1A1 | |
| SCHEMBL4136041 | 0.81 | HTT (0.57) | HTTCYP2C9ALOX15HSD17B10HRH3 | |
| SCHEMBL13115535 | 0.81 | HTT (0.57) | HTTCYP2C9ALOX15HSD17B10HRH3 | |
| SCHEMBL11523316 | 0.80 | ALDH1A1 (0.41) | HTTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL4144775 | 0.80 | ALDH1A1 (0.55) | HTTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1472855 | 0.78 | GFER (0.64) | HTTCYP2C9ALOX15HSD17B10HRH3 | |
| SCHEMBL8263606 | 0.78 | ALDH1A1 (0.63) | HTTCYP2C9ALOX15HSD17B10HRH3 | |
| SCHEMBL11479737 | 0.78 | HTT (0.57) | HTTCYP2C9ALOX15HSD17B10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174221-A1 | PROCESS FOR PRODUCING AN AMINE IN A SOLVENT SYSTEM CONTAINING WATER | RHODIA OPERATIONS (FR) | 2019-09-19 | — | — | WO | disclosed |
| CN-105622554-A | Method for preparing 2-hydroxymethyl-5-amine methyl furan compound by fructose | DALIAN INST CHEMICAL PHYSICS CAS | 2016-06-01 | — | — | CN | disclosed |
| CN-105503791-A | 2-hydroxymethyl-5-aminomethyl-furan compound synthesis method | DALIAN INST CHEMICAL PHYSICS CAS | 2016-04-20 | — | — | CN | disclosed |
| US-20090054397-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND | OHI NORIHITO | 2009-02-26 | — | — | US | disclosed |
| US-20090054397-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND | OHI NORIHITO | 2009-02-26 | — | — | US | disclosed |
| US-20090054397-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND | OHI NORIHITO | 2009-02-26 | — | — | US | disclosed |
| US-7429609-B2 | Pyrazole compound and medicinal composition containing the same | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-30 | — | — | US | disclosed |
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
| US-20050208582-A1 | Pyrazole compounds and pharmaceutical compositions comprising the compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| CN-1656079-A | Pyrazole compounds and pharmaceutical compositions containing the same | EISAI CO LTD (JP) | 2005-08-17 | — | — | CN | disclosed |
| EP-1510516-A1 | PYRAZOLE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054397-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND | CNKSR1, NR3C2, CSNK2B | HTT 3425/4885CYP2C9 908/4885ALOX15 3178/4885 |
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | CNKSR1, NR3C2, CSNK2B | HTT 3942/4885CYP2C9 1578/4885ALOX15 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.