SCHEMBL4143262

SCHEMBL4143262

Oc1cc(Cl)cc(OCCCCCCOc2ccc(C(F)(F)F)cn2)c1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
KMT2A Q03164 1/20 0.41
MAPK1 P28482 1/20 0.41
RXRA P19793 5/20 0.41
GRIN1 Q05586 5/20 0.41
GRIN2B Q13224 5/20 0.41
RAB9A P51151 1/20 0.40
THRB P10828 1/20 0.39
LIPE Q05469 3/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4126578 0.96 L3MBTL1 (0.47) L3MBTL1TDP1MRGPRX4KMT2AMAPK1
SCHEMBL4143275 0.84 L3MBTL1 (0.39) L3MBTL1TDP1MRGPRX4KMT2AMAPK1
SCHEMBL7076311 0.84 MRGPRX4 (0.46) L3MBTL1TDP1MRGPRX4KMT2AMAPK1
SCHEMBL7078746 0.84 MRGPRX4 (0.46) L3MBTL1TDP1MRGPRX4KMT2AMAPK1
SCHEMBL7716832 0.83 L3MBTL1 (0.40) L3MBTL1TDP1MRGPRX4KMT2AMAPK1
SCHEMBL4143051 0.82 MAPK1 (0.46) L3MBTL1TDP1MRGPRX4KMT2AMAPK1
SCHEMBL7073751 0.82 MRGPRX4 (0.47) L3MBTL1TDP1MRGPRX4KMT2AMAPK1
SCHEMBL27480518 0.81 KMT2A (0.43) L3MBTL1MRGPRX4KMT2AMAPK1RAB9A
SCHEMBL27480517 0.81 KMT2A (0.43) L3MBTL1MRGPRX4KMT2AMAPK1RAB9A
SCHEMBL4139449 0.80 L3MBTL1 (0.40) L3MBTL1TDP1MRGPRX4KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090209598-A1 Resorcine Derivatives and Their Use as Pesticides BASF SE (DE) 2009-08-20 US disclosed
EP-1951649-A2 RESORCINE DERIVATIVES AND THEIR USE AS PESTICIDES BASF SE (DE) 2008-08-06 EP disclosed
WO-2007054558-A2 RESORCINE DERIVATIVES AND THEIR USE AS PESTICIDES BASF SE (DE) 2007-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209598-A1 Resorcine Derivatives and Their Use as Pesticides NR2C2, NR2E1, NR4A2 L3MBTL1 476/4885TDP1 3818/4885MRGPRX4 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.