SCHEMBL4143791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4136985	0.82	HSD17B14 (0.54)	IGFBP3CES2CES1KMT2AMEN1
	SCHEMBL27536109	0.74	CES2 (0.53)	CES2CES1PARP1KMT2AHDAC1
	SCHEMBL2865154	0.72	CES2 (0.51)	CES2CES1PARP1KMT2AMEN1
	SCHEMBL4136803	0.72	CES2 (0.50)	IGFBP3CES2CES1PARP1KMT2A
	SCHEMBL1258944	0.71	CES2 (0.74)	CES2CES1PARP1KMT2AMEN1
	SCHEMBL2705684	0.69	CES2 (0.71)	CES2CES1PARP1KMT2AMEN1
	Hydrochloric Acid SCHEMBL27733562	0.69	CES2 (0.71)	CES2CES1PARP1KMT2AMEN1
	SCHEMBL18412841	0.69	KCNQ3 (0.41)	KCNQ3KCNQ2RAB9A
	SCHEMBL2858165	0.69	CES2 (0.50)	CES2CES1PARP1KMT2AMEN1
	SCHEMBL3038873	0.68	CES2 (0.63)	CES2CES1PARP1KMT2AHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.