Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144329 | 1.00 | MET (0.38) | METGPR84P2RY12ALOX5APMCHR1 | |
| SCHEMBL4145072 | 0.95 | P2RY12 (0.39) | METGPR84P2RY12MAPK14SMO | |
| SCHEMBL4145071 | 0.95 | P2RY12 (0.39) | METGPR84P2RY12MAPK14SMO | |
| SCHEMBL4146064 | 0.92 | PRKCA (0.38) | METGPR84ALOX5APMCHR1MAPK14 | |
| SCHEMBL4146072 | 0.92 | PRKCA (0.38) | METGPR84ALOX5APMCHR1MAPK14 | |
| SCHEMBL4143500 | 0.92 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4143504 | 0.92 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4145227 | 0.91 | HRH3 (0.33) | METGPR84ALOX5APMCHR1SMO | |
| SCHEMBL4145232 | 0.91 | HRH3 (0.33) | METGPR84ALOX5APMCHR1SMO | |
| SCHEMBL4144460 | 0.90 | PRMT5 (0.35) | GPR84HRH3ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | IDO1, IDO2, ZC3HAV1 | MET 2461/4885GPR84 2204/4885P2RY12 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.