SCHEMBL4144463

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4160058	0.93	L3MBTL1 (0.41)	NR1H2NR1H3L3MBTL1MAPTMAPK1
	SCHEMBL4145083	0.91	AR (0.47)	L3MBTL1MAPTNPC1RAB9AAR
	SCHEMBL4139876	0.90	AR (0.40)	NR1H2NR1H3ARPGR
	SCHEMBL4137799	0.88	GRM5 (0.43)	NR1H2NR1H3L3MBTL1ARCTSS
	SCHEMBL4153574	0.86	AR (0.40)	ARPGR
	SCHEMBL4147167	0.84	S1PR1 (0.44)	NR1H2NR1H3MAPTNPC1RAB9A
	SCHEMBL4137720	0.83	NR1H2 (0.46)	NR1H2NR1H3L3MBTL1MAPTNPC1
	SCHEMBL4137903	0.83	AR (0.40)	L3MBTL1ARPGRKDM4EALDH1A1
	SCHEMBL4153700	0.83	AR (0.38)	ARPGR
	SCHEMBL4136947	0.83	AR (0.43)	ARNPSR1PGRPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.