Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144911 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4139797 | 0.71 | KMT2A (0.37) | KDM4EALDH1A1HPGD | |
| SCHEMBL3244153 | 0.65 | SRD5A2 (0.43) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| SCHEMBL4825624 | 0.63 | CA12 (0.35) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| SCHEMBL3075059 | 0.62 | TBXA2R (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4826413 | 0.62 | MAPK8 (0.34) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| SCHEMBL4831483 | 0.61 | SMN1; SMN2 (0.36) | KDM4E | |
| SCHEMBL4830100 | 0.61 | KDM4E (0.37) | KDM4EALDH1A1HPGDENPP2HSD17B10 | |
| SCHEMBL4830030 | 0.61 | SLC22A12 (0.35) | — | |
| SCHEMBL4828066 | 0.61 | GAA (0.34) | KDM4EALDH1A1HPGDENPP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | IDO1, IDO2, ZC3HAV1 | KDM4E 2269/4885ALDH1A1 754/4885HPGD 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.