Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112838 | 0.79 | KDM1A (0.59) | KDM1AMAOBMEN1KMT2AAKR1B1 | |
| SCHEMBL1101137 | 0.79 | KDM1A (0.59) | KDM1AMAOBMEN1KMT2AAKR1B1 | |
| SCHEMBL6440070 | 0.76 | KDM1A (0.56) | KDM1AMAOBMEN1KMT2AAKR1B1 | |
| SCHEMBL9396129 | 0.76 | KDM1A (0.56) | KDM1AMAOBMEN1KMT2AAKR1B1 | |
| SCHEMBL3539945 | 0.76 | KDM1A (0.56) | KDM1AMAOBMEN1KMT2AAKR1B1 | |
| SCHEMBL6917152 | 0.76 | KDM1A (0.47) | KDM1AMEN1KMT2AAKR1B1TSHR | |
| SCHEMBL5369769 | 0.76 | KDM1A (0.56) | KDM1AMAOBMEN1KMT2AAKR1B1 | |
| SCHEMBL643388 | 0.76 | KDM1A (0.66) | KDM1AMAOBMEN1KMT2AAKR1B1 | |
| SCHEMBL1273553 | 0.76 | KDM1A (0.66) | KDM1AMAOBMEN1KMT2AAKR1B1 | |
| SCHEMBL11696762 | 0.74 | KDM1A (0.54) | KDM1AMEN1KMT2AAKR1B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757875-B | Dihydrobenzofuran and indene analogs as myocardial segment inhibitors | 赛特凯恩蒂克公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-106572658-B | Molecule and relative intermediate, composition and method with certain disinsection efficiencies | 美国陶氏益农公司 | 2019-11-08 | — | — | CN | disclosed |
| CN-106748809-B | A method of adjacent halogen arylamine is prepared based on C-H activation arylamine class | 浙江工业大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-106748809-A | A kind of method that adjacent halogen arylamine is prepared based on C H activation arylamine classes | 浙江工业大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106572658-A | Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto | 美国陶氏益农公司 | 2017-04-19 | — | — | CN | disclosed |
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | MCHARDY STANTON FURST | 2009-06-25 | — | — | US | disclosed |
| EP-2007749-A2 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | Pfizer Products Inc. (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105053-A2 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | HRH3, HRH4, HRH1 | KDM1A 4096/4885MAOB 477/4885MEN1 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.