Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396129 | 1.00 | KDM1A (0.56) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL2114349 | 0.88 | KDM1A (0.50) | KDM1AMAOBTSHRSIGMAR1TP53 | |
| SCHEMBL1101137 | 0.79 | KDM1A (0.59) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL30112838 | 0.79 | KDM1A (0.59) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL24124824 | 0.76 | KDM1A (0.56) | KDM1AMEN1KMT2AAKR1B1TSHR | |
| SCHEMBL4144872 | 0.76 | KDM1A (0.56) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL6440070 | 0.76 | KDM1A (0.56) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL1273553 | 0.76 | KDM1A (0.66) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL643388 | 0.76 | KDM1A (0.66) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL3539945 | 0.76 | KDM1A (0.56) | KDM1AMEN1KMT2AAKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781662-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | Pfizer, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018725-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-02-23 | — | — | WO | disclosed |