Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904515 | 0.83 | TACR1 (0.41) | MMP2MMP9TACR1CYP2D6KMT2A | |
| SCHEMBL3953038 | 0.83 | TACR1 (0.41) | MMP2MMP9TACR1CYP2D6KMT2A | |
| SCHEMBL4145234 | 0.81 | TACR1 (0.42) | MMP2MMP9TACR1CYP2D6KMT2A | |
| SCHEMBL4062789 | 0.80 | TACR1 (0.44) | MMP2MMP9TACR1CYP2D6KMT2A | |
| SCHEMBL13904509 | 0.76 | MMP9 (0.43) | MMP2MMP9TACR1CYP2D6KMT2A | |
| SCHEMBL3947792 | 0.76 | MMP9 (0.43) | MMP2MMP9TACR1CYP2D6KMT2A | |
| SCHEMBL4632722 | 0.75 | ITGB2 (0.41) | MMP2MMP9TACR1KMT2AMAPT | |
| SCHEMBL4633717 | 0.75 | HDAC3 (0.44) | MMP2MMP9TACR1KMT2AMAPT | |
| SCHEMBL4632690 | 0.75 | HDAC3 (0.44) | MMP2MMP9TACR1KMT2AMAPT | |
| SCHEMBL4737837 | 0.74 | ITGB2 (0.43) | MMP2MMP9TACR1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069328-A1 | ALPHA-ALKYL SUBSTITUTED N-ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AG (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069328-A1 | ALPHA-ALKYL SUBSTITUTED N-ACYLTRYPTOPHANOLS | FSHR, GNRHR, TPH1 | MMP2 3861/4885MMP9 4077/4885TACR1 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.