Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145410 | 1.00 | EBP (0.38) | EBPSIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL1689612 | 0.93 | EBP (0.42) | EBPSIGMAR1MEN1KMT2ADRD2 | |
| SCHEMBL1689615 | 0.93 | EBP (0.42) | EBPSIGMAR1MEN1KMT2ADRD2 | |
| SCHEMBL5769219 | 0.89 | AVPR1A (0.40) | EBPSIGMAR1DRD2LMNAAVPR1A | |
| SCHEMBL1689602 | 0.85 | EBP (0.39) | EBPSIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL1689711 | 0.85 | DRD2 (0.43) | EBPSIGMAR1MEN1KMT2ANPSR1 | |
| SCHEMBL1689605 | 0.85 | EBP (0.39) | EBPSIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL1689609 | 0.85 | DRD2 (0.43) | EBPSIGMAR1MEN1KMT2ANPSR1 | |
| 4-Chloroaniline SCHEMBL2915266 | 0.81 | DRD2 (0.40) | EBPSIGMAR1MEN1KMT2ANPSR1 | |
| SCHEMBL3815207 | 0.78 | OPRD1 (0.41) | EBPSIGMAR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846907-B2 | Spiro-condensed indoline derivatives as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2014-09-30 | — | — | US | disclosed |
| US-20130046091-A1 | SPIRO-CONDENSED INDOLINE DERIVATIVES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-21 | — | — | US | disclosed |
| US-8299058-B2 | Spiro-condensed indoline derivatives as pesticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-30 | — | — | US | disclosed |
| US-20090042859-A1 | SPIRO-CONDENSED INDOLINE DERIVATIVES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-02-12 | — | — | US | disclosed |
| EP-1697376-B1 | SPIRO-CONDENSED INDOLINE DERIVATIVES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042859-A1 | SPIRO-CONDENSED INDOLINE DERIVATIVES AS PESTICIDES | CHRM1, CHRM2, RO60 | EBP 2628/4885SIGMAR1 615/4885MEN1 1098/4885 |
| US-20130046091-A1 | SPIRO-CONDENSED INDOLINE DERIVATIVES AS PESTICIDES | CHRM1, CHRM2, CHRM3 | EBP 2712/4885SIGMAR1 435/4885MEN1 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.