Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145806 | 1.00 | PRKCA (0.38) | PRKCAMMP12NR1I2PTGER4CNR2 | |
| SCHEMBL4157782 | 0.94 | PRKCA (0.38) | PRKCAMMP12PTGER4ALDH1A1KMT2A | |
| SCHEMBL4157786 | 0.94 | PRKCA (0.38) | PRKCAMMP12PTGER4ALDH1A1KMT2A | |
| SCHEMBL4139270 | 0.91 | CNR2 (0.38) | PRKCAMMP12NR1I2CNR2CNR1 | |
| SCHEMBL4156129 | 0.91 | CNR2 (0.38) | PRKCAMMP12NR1I2CNR2CNR1 | |
| SCHEMBL4139268 | 0.91 | CNR2 (0.38) | PRKCAMMP12NR1I2CNR2CNR1 | |
| SCHEMBL4156124 | 0.91 | CNR2 (0.38) | PRKCAMMP12NR1I2CNR2CNR1 | |
| SCHEMBL4149254 | 0.90 | CNR2 (0.37) | PRKCAMMP12CNR2CNR1ALDH1A1 | |
| SCHEMBL4149257 | 0.90 | CNR2 (0.37) | PRKCAMMP12CNR2CNR1ALDH1A1 | |
| SCHEMBL895934 | 0.88 | PRKCA (0.49) | PRKCAMMP12NR1I2PTGER4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | IDO1, IDO2, ZC3HAV1 | PRKCA 4320/4885MMP12 3563/4885NR1I2 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.