Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156129 | 1.00 | CNR2 (0.38) | CNR2NAMPTPARP1PRKCAMMP12 | |
| SCHEMBL4150441 | 0.94 | CCR3 (0.34) | NAMPTPRKCAMMP12NR1I2CCR3 | |
| SCHEMBL4150447 | 0.94 | CCR3 (0.34) | NAMPTPRKCAMMP12NR1I2CCR3 | |
| SCHEMBL4139268 | 0.94 | CNR2 (0.38) | CNR2NAMPTPARP1PRKCAMMP12 | |
| SCHEMBL4139270 | 0.94 | CNR2 (0.38) | CNR2NAMPTPARP1PRKCAMMP12 | |
| SCHEMBL4149257 | 0.92 | CNR2 (0.37) | CNR2PRKCAMMP12CNR1ALDH1A1 | |
| SCHEMBL4149254 | 0.92 | CNR2 (0.37) | CNR2PRKCAMMP12CNR1ALDH1A1 | |
| SCHEMBL4145806 | 0.91 | PRKCA (0.38) | CNR2PRKCAMMP12CNR1NR1I2 | |
| SCHEMBL4145802 | 0.91 | PRKCA (0.38) | CNR2PRKCAMMP12CNR1NR1I2 | |
| SCHEMBL4139150 | 0.89 | CNR2 (0.39) | CNR2TSHRCNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | IDO1, IDO2, ZC3HAV1 | CNR2 248/4885NAMPT 3111/4885PARP1 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.