SCHEMBL4146320

SCHEMBL4146320

CC(C)NCCCCCC(=O)CNC(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPK1 P28482 2/20 0.37
MEN1 O00255 1/20 0.37
EPHX1 P07099 1/20 0.35
ADRA1A P35348 1/20 0.34
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 2/20 0.34
HAO1 Q9UJM8 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
SOAT1 P35610 1/20 0.33
PAOX Q6QHF9 1/20 0.32
MAPT P10636 1/20 0.32
PRMT1 Q99873 1/20 0.32
HIF1A Q16665 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
EPHX2 P34913 1/20 0.31
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22306368 0.84 KMT2A (0.41) FAAHKMT2AMAPK1MEN1EPHX1
SCHEMBL14450656 0.83 DPP4 (0.32) ALDH1A1ARG1ARG2
SCHEMBL21575554 0.82 FAAH (0.52) FAAHKMT2AMAPK1MEN1ALDH1A1
SCHEMBL25546773 0.82 MAPK1 (0.38) FAAHKMT2AMAPK1MEN1EPHX1
SCHEMBL329452 0.81 ARG1 (0.35) FAAHKMT2AMAPK1MEN1EPHX1
SCHEMBL24797080 0.80 KDM4C (0.42) FAAHKMT2AMAPK1MEN1SOAT1
SCHEMBL25453230 0.79 PAOX (0.52) FAAHKMT2AMAPK1MEN1EPHX1
SCHEMBL25090250 0.79 PAOX (0.52) FAAHKMT2AMAPK1MEN1EPHX1
SCHEMBL24359721 0.79 MEN1 (0.39) FAAHKMT2AMAPK1MEN1EPHX1
SCHEMBL25453158 0.79 PAOX (0.52) FAAHKMT2AMAPK1MEN1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8071676-B2 Modified polymer and composition containing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-12-06 US disclosed
US-20090124730-A1 Modified polymer and composition containing the same ASAHI KASEI CHEMICALS CORPORATION 2009-05-14 US disclosed