Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12020461 | 0.80 | TSHR (0.36) | TSHRPPARD | |
| SCHEMBL12020457 | 0.77 | TSHR (0.33) | TSHRPPARD | |
| SCHEMBL24540306 | 0.75 | PPARD (0.39) | TSHRPPARD | |
| SCHEMBL4147004 | 0.73 | TSHR (0.40) | TSHRPPARDSMN1; SMN2HPGDALOX15 | |
| SCHEMBL15438884 | 0.72 | TSHR (0.39) | TSHRPPARDSMN1; SMN2HPGDALOX15 | |
| SCHEMBL28511812 | 0.71 | TSHR (0.50) | TSHRPPARDSMN1; SMN2HPGDALOX15 | |
| SCHEMBL13421215 | 0.71 | TSHR (0.46) | TSHRPPARDSMN1; SMN2HPGDALOX15 | |
| SCHEMBL12232722 | 0.70 | NQO1 (0.36) | TSHRSMN1; SMN2TDP1 | |
| SCHEMBL4134682 | 0.70 | GAA (0.39) | TSHRSMN1; SMN2TDP1 | |
| SCHEMBL8488780 | 0.68 | NPSR1 (0.41) | TSHRHPGDMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120114974-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | NATIONAL SCIENCE FOUNDATION | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114974-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | EFNA1, PHOSPHO1, EPHA6 | TSHR 4110/4885PPARD 2434/4885SMN1; SMN2 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.