Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135818 | 0.77 | PPARD (0.37) | TSHRPPARD | |
| SCHEMBL13421215 | 0.76 | TSHR (0.46) | TSHRPPARDSMN1; SMN2HPGDALOX15 | |
| SCHEMBL10072425 | 0.76 | PPARD (0.36) | TSHRPPARD | |
| SCHEMBL9499680 | 0.75 | TSHR (0.60) | TSHRPPARDTP53TDP1 | |
| SCHEMBL6311761 | 0.74 | TSHR (0.48) | TSHRPPARDSMN1; SMN2HPGDALOX15 | |
| SCHEMBL4146949 | 0.73 | TSHR (0.43) | TSHRPPARDSMN1; SMN2HPGDALOX15 | |
| SCHEMBL7940743 | 0.73 | TSHR (0.57) | TSHRPPARDTP53TDP1 | |
| SCHEMBL4147009 | 0.72 | PTPN1 (0.31) | — | |
| SCHEMBL4150229 | 0.69 | TSHR (0.48) | TSHRMAPK1NPSR1 | |
| SCHEMBL9304075 | 0.69 | TSHR (0.52) | TSHRPPARDSMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120114974-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | NATIONAL SCIENCE FOUNDATION | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114974-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | EFNA1, PHOSPHO1, EPHA6 | TSHR 4110/4885PPARD 2434/4885SMN1; SMN2 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.