SCHEMBL414705

SCHEMBL414705

O=c1ccn([C@@]2(Cl)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.44
SLC28A2 O43868 1/20 0.44
SLC29A1 Q99808 1/20 0.44
SLC28A3 Q9HAS3 1/20 0.44
P2RY6 Q15077 9/20 0.39
P2RY14 Q15391 1/20 0.34
DUT P33316 3/20 0.33
POLA1 P09884 1/20 0.33
P2RY2 P41231 2/20 0.33
P2RY4 P51582 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9393373 0.92 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL28786348 0.84 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL51723 0.84 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL1094026 0.83 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL27451524 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL27703606 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2242410 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
Hydrochloric Acid SCHEMBL27782735 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL65485 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2009955 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200385789-A1 METHODS OF ASSESSING TELOMERES CHILDREN'S MEDICAL RESEARCH INSTITUTE (AU) 2020-12-10 US claimed
EP-3676609-A1 METHODS OF ASSESSING TELOMERES Children's Medical Research Institute (AU) 2020-07-08 EP claimed
WO-2019040993-A1 METHODS OF ASSESSING TELOMERES CHILDREN'S MEDICAL RESEARCH INSTITUTE (AU) 2019-03-07 WO claimed
US-9644238-B2 Methods of isolating non-senescent cardiac stem cells and uses thereof AUTOLOGOUS REGENERATION, LLC (US) 2017-05-09 US claimed
CN-102753526-B Pyridinone hydroxycyclopentyl carboxamides: HIV integrase inhibitors with therapeutic applications UNIV GEORGIA 2014-11-26 CN claimed
US-20140051077-A1 METHODS OF ISOLATING NON-SENESCENT CARDIAC STEM CELLS AND USES THEREOF AUTOLOGOUS, LLC (US) 2014-02-20 US claimed
EP-2635292-A1 METHODS OF ISOLATING NON-SENESCENT CARDIAC STEM CELLS AND USES THEREOF Autologous, LLC (US) 2013-09-11 EP claimed
US-8512696-B2 Methods of isolating non-senescent cardiac stem cells and uses thereof AUTOLOGOUS, LLC (US) 2013-08-20 US claimed
WO-2012061491-A1 METHODS OF ISOLATING NON-SENESCENT CARDIAC STEM CELLS AND USES THEREOF ANVERSA PIERO (US) 2012-05-10 WO claimed
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US claimed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US claimed
US-20030229004-A1 Modulation of tumor cells using BER inhibitors in combination with a sensitizing agent and DSBR inhibitors PANGENE CORPORATION 2003-12-11 US claimed
WO-1996021665-A1 TURCASARINS, NOVEL EXPANDED PORPHYRINS, AND USES THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1996-07-18 WO claimed
US-4780406-A Flow cytometric measurement of total DNA and incorporated halodeoxyuridine THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1988-10-25 US claimed
US-4585736-A Flow cytometric measurement of total DNA and incorporated halodeoxyuridine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1986-04-29 US claimed
US-20250207177-A1 METHODS, COMPOSITIONS AND DEVICES FOR SPREADING OF CHROMATIN FIBERS ERASMUS UNIVERSITY MEDICAL CENTER (NL) 2025-06-26 US disclosed
US-12246017-B2 Replication stress pathway agent compositions and methods for treating cancer BOUNDLESS BIO, INC. (US) 2025-03-11 US disclosed
US-6020146-A Carcinogenicity testing system THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) 2000-02-01 US disclosed
US-5594136-A USEFUL IN THE SEPARATION OF NEUTRAL AND ANIONIC SPECIES, PHOSPHATE ESTER HYDROLYSIS, MAGNETIC RESONANCE IMAGING AND PHOTODYNAMIC THERAPY PHARMACYCLICS, INC. (US) 1997-01-14 US disclosed
WO-1996013552-A2 SUBSTITUTED UNSYMMETRICAL CYANINE DYES WITH SELECTED PERMEABILITY MOLECULAR PROBES, INC. (US) 1996-05-09 WO disclosed