Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26699604 | 0.91 | KCNA5 (0.38) | KCNA5KCNJ5KCNJ3SCN5AKCND3 | |
| SCHEMBL25685120 | 0.89 | ALDH1A1 (0.35) | KCNA5KCNJ5KCNJ3SCN5AKCND3 | |
| SCHEMBL7571504 | 0.82 | KCNA5 (0.38) | KCNA5KCNJ5KCNJ3SCN5AKCND3 | |
| SCHEMBL25761576 | 0.82 | KCNA5 (0.38) | KCNA5KCNJ5KCNJ3SCN5AKCND3 | |
| SCHEMBL24292469 | 0.74 | KCNA5 (0.50) | KCNA5KCNJ5KCNJ3SCN5AKCND3 | |
| SCHEMBL7961260 | 0.74 | — | — | |
| SCHEMBL26045938 | 0.74 | — | — | |
| SCHEMBL20753133 | 0.74 | LMNA (0.42) | KCNA5KCNJ5KCNJ3SCN5AKCND3 | |
| SCHEMBL30353890 | 0.73 | TDP1 (0.41) | KCNA5TDP1TSHR | |
| SCHEMBL13452838 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036322-A1 | Leukocyte Adsorbing Material | UNIVERSITY OF SOUTHHAMPTON (GB) | 2009-02-05 | — | — | US | disclosed |
| EP-1776184-A1 | LEUKOCYTE ADSORBING MATERIAL | UNIVERSITY OF SOUTHAMPTON (GB) | 2007-04-25 | — | — | EP | disclosed |
| WO-2005113136-A1 | LEUKOCYTE ADSORBING MATERIAL | UNIVERSITY OF SOUTHAMPTON (GB) | 2005-12-01 | — | — | WO | disclosed |