⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376013 | 0.91 | — | — | |
| SCHEMBL2921190 | 0.77 | — | — | |
| SCHEMBL9243242 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL3333990 | 0.68 | — | — | |
| SCHEMBL1002310 | 0.68 | — | — | |
| SCHEMBL370773 | 0.67 | DUT (0.30) | — | |
| SCHEMBL7551845 | 0.67 | — | — | |
| SCHEMBL6266623 | 0.65 | — | — | |
| SCHEMBL17359792 | 0.65 | — | — | |
| SCHEMBL647513 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438112-B1 | USE OF A PARTICULAR ORGANOSILICIUM COMPOUND AS A COUPLING AGENT IN AN ELASTOMER COMPOSITION COMPRISING AN INORGANIC REINFORCING FILLER | RHODIA OPERATIONS (FR) | 2020-03-18 | — | — | EP | disclosed |
| US-8980392-B2 | Use of a specific functionalised organosilicon compound as a coupling agent in an isoprene elastomer composition including a reinforcing inorganic filler | RHODIA OPERATIONS (FR) | 2015-03-17 | — | — | US | disclosed |
| US-8664311-B2 | Rubber compositions comprising two different coupling agents and also inorganic fillers | RHODIA CHIMIE (FR) | 2014-03-04 | — | — | US | disclosed |
| US-20120225233-A1 | USE OF A SPECIFIC FUNCTIONALISED ORGANOSILICON COMPOUND AS A COUPLING AGENT IN AN ISOPRENE ELASTOMER COMPOSITION INCLUDING A REINFORCING INORGANIC FILLER | RHODIA OPERATIONS (FR) | 2012-09-06 | — | — | US | disclosed |
| US-20090215952-A1 | Rubber compositions comprising two different coupling agents and also inorganic fillers | RHODIA CHIMIE (FR) | 2009-08-27 | — | — | US | disclosed |
| US-7217751-B2 | Diene elastomer and filler; vulcanization | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2007-05-15 | — | — | US | disclosed |
| US-20040132880-A1 | Diene elastomer and filler; vulcanization | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2004-07-08 | — | — | US | disclosed |
| CN-1501959-A | Tyre and running tread comprising as coupling agent a bis-alkoxysilane tetrasulphide | �����ּ�����˾ | 2004-06-02 | — | — | CN | disclosed |