Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148073 | 1.00 | ADRB2 (0.42) | ADRB2CHRM3CHRM2CHRM1TRPV1 | |
| SCHEMBL4719214 | 0.94 | ADRB2 (0.37) | ADRB2CHRM3 | |
| SCHEMBL4155533 | 0.89 | ADRB2 (0.47) | ADRB2CHRM3CHRM2CHRM1TRPV1 | |
| SCHEMBL4156614 | 0.85 | CHRM3 (0.61) | ADRB2CHRM3CHRM2CHRM1 | |
| SCHEMBL4151178 | 0.83 | ADRB2 (0.56) | ADRB2CHRM3CHRM2CHRM1 | |
| SCHEMBL4166395 | 0.82 | ADRB2 (0.51) | ADRB2CHRM3CHRM2CHRM1 | |
| SCHEMBL4336215 | 0.82 | ADRB2 (0.67) | ADRB2CHRM3 | |
| SCHEMBL4164154 | 0.79 | ADRB2 (0.67) | ADRB2CHRM3 | |
| SCHEMBL4345217 | 0.79 | ADRB2 (0.65) | ADRB2CHRM3 | |
| SCHEMBL4142367 | 0.78 | ADRB2 (0.68) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612084-B2 | Amine derivatives for the treatment of asthma and COPD | PFIZER INC (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090253739-A1 | Amine Derivatives | PFIZER INC | 2009-10-08 | — | — | US | disclosed |
| US-20090253739-A1 | Amine Derivatives | PFIZER INC | 2009-10-08 | — | — | US | disclosed |
| US-20070265303-A1 | Amine derivatives | PFIZER LIMITED | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265303-A1 | Amine derivatives | HNMT, HRH4, CMA1 | ADRB2 93/4885CHRM3 169/4885CHRM2 142/4885 |
| US-20090253739-A1 | Amine Derivatives | HNMT, HRH4, CMA1 | ADRB2 93/4885CHRM3 169/4885CHRM2 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.