SCHEMBL4148271

SCHEMBL4148271

c1ccc(-c2cccc3cccnc23)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.60
TSHR P16473 2/20 0.60
MAPT P10636 2/20 0.60
LMNA P02545 2/20 0.60
KDM4E B2RXH2 2/20 0.60
GMNN O75496 1/20 0.60
TP53 P04637 1/20 0.60
HSP90AA1 P07900 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2D6 P10635 1/20 0.60
MMP9 P14780 1/20 0.60
ALOX15 P16050 1/20 0.60
NFKB1 P19838 1/20 0.60
MMP8 P22894 1/20 0.60
CCR1 P32246 1/20 0.60
THPO P40225 1/20 0.60
MTOR P42345 1/20 0.60
HTT P42858 1/20 0.60
MMP13 P45452 1/20 0.60
CCR5 P51681 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27816291 0.98 MMP2 (0.58) MMP2TSHRMAPTLMNAKDM4E
SCHEMBL30592746 0.96 MMP2 (0.56) MMP2TSHRMAPTLMNAKDM4E
Water SCHEMBL28036087 0.96 MMP2 (0.56) MMP2TSHRMAPTLMNAKDM4E
SCHEMBL12074320 0.96 MMP2 (0.56) MMP2TSHRMAPTLMNAKDM4E
SCHEMBL12580425 0.91 MMP2 (0.50) MMP2TSHRMAPTLMNAKDM4E
SCHEMBL12580374 0.91 MMP2 (0.50) MMP2TSHRMAPTLMNAKDM4E
SCHEMBL12580436 0.89 MMP2 (0.48) MMP2TSHRMAPTLMNAKDM4E
SCHEMBL12580382 0.89 MMP2 (0.48) MMP2TSHRMAPTLMNAKDM4E
SCHEMBL28105390 0.89 LMNA (0.48) MMP2TSHRMAPTLMNAKDM4E
SCHEMBL24621910 0.88 CCR1 (0.47) MMP2TSHRMAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322227-B Divalent platinum or palladium metal complex phosphorescent materials and devices based on coordination of 8-phenylquinoline and derivatives thereof 浙江工业大学 2024-02-02 CN claimed
CN-115322227-A Divalent platinum or palladium metal complex phosphorescent material and device based on 8-phenylquinoline and derivative coordination thereof 浙江工业大学 2022-11-11 CN claimed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US claimed
US-20250122422-A1 CYCLIC TETRADENTATE METAL PLATINUM (II) COMPLEX PHOSPHORESCENT MATERIAL AND USE THEREOF ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2025-04-17 US disclosed
US-20250122422-A1 CYCLIC TETRADENTATE METAL PLATINUM (II) COMPLEX PHOSPHORESCENT MATERIAL AND USE THEREOF ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2025-04-17 US disclosed
CN-116854742-B Platinum metal complex, organic photoelectric device and display or lighting device 浙江工业大学 2025-02-14 CN disclosed
CN-116854742-B Platinum metal complex, organic photoelectric device and display or lighting device 浙江工业大学 2025-02-14 CN disclosed
EP-4506352-A1 PLATINUM COMPLEX, ORGANIC PHOTOELECTRIC DEVICE, AND DISPLAY OR LIGHTING DEVICE Zhejiang University of Technology (CN) 2025-02-12 EP disclosed
EP-4506352-A1 PLATINUM COMPLEX, ORGANIC PHOTOELECTRIC DEVICE, AND DISPLAY OR LIGHTING DEVICE Zhejiang University of Technology (CN) 2025-02-12 EP disclosed
CN-118406085-B Four-tooth ring metal platinum (II) complex phosphorescent material and application thereof 浙江工业大学 2024-11-05 CN disclosed
CN-118406085-B Four-tooth ring metal platinum (II) complex phosphorescent material and application thereof 浙江工业大学 2024-11-05 CN disclosed
EP-1093372-A1 CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS Elan Pharmaceuticals, Inc. (US) 2001-04-25 EP disclosed
EP-1089977-A1 COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS Elan Pharmaceuticals, Inc. (US) 2001-04-11 EP disclosed
EP-1089981-A1 COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS. Elan Pharmaceuticals, Inc. (US) 2001-04-11 EP disclosed
WO-1999066934-A1 CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS ELAN PHARMACEUTICALS, INC. (US) 1999-12-29 WO disclosed
WO-1999067219-A1 COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS ELAN PHARMACEUTICALS, INC. (US) 1999-12-29 WO disclosed
WO-1999067220-A1 COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS ELAN PHARMACEUTICALS, INC. (US) 1999-12-29 WO disclosed
EP-0691966-B1 QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS SYNTEX INC (US) 1998-09-09 EP disclosed
CN-87102669-A Fiberboard and manufacture method thereof 1987-12-30 CN disclosed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US disclosed