Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | BCL9 | O00512 | 4/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148279 | 1.00 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KCNH2BCL9 | |
| SCHEMBL4126638 | 0.92 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2BCL9 | |
| SCHEMBL4126641 | 0.92 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2BCL9 | |
| SCHEMBL4145162 | 0.88 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2HTR1A | |
| SCHEMBL4145168 | 0.88 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL4136523 | 0.87 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2BCL9 | |
| Hydrochloric Acid SCHEMBL4136521 | 0.87 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2BCL9 | |
| SCHEMBL4137355 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2BCL9 | |
| SCHEMBL4137362 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2BCL9 | |
| SCHEMBL4135569 | 0.86 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3KCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215857-A1 | Therapeutic Pyrrolidines | PFIZER PRODUCTS INC. (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215857-A1 | Therapeutic Pyrrolidines | OPRL1, HTR5A, OPRD1 | SLC6A2 28/4885SLC6A4 18/4885SLC6A3 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.