SCHEMBL4148707

SCHEMBL4148707

CCCCOC(=O)OC(=O)NN

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
EPHX1 P07099 1/20 0.44
ATM Q13315 1/20 0.44
ACHE P22303 9/20 0.43
NAAA Q02083 1/20 0.42
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 2/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NPC1 O15118 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.40
HCAR2 Q8TDS4 1/20 0.39
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283132 0.84
Hydrazine SCHEMBL28106872 0.82 EPHX1 (0.53) ALDH1A1EPHX1ATMACHEHPGD
SCHEMBL40274 0.81 ALDH1A1 (0.61) ALDH1A1EPHX1ATMACHENAAA
SCHEMBL28667866 0.81 ACHE (0.47) ALDH1A1EPHX1ATMACHENAAA
SCHEMBL4313949 0.79 ALDH1A1 (0.58) ALDH1A1EPHX1ATMACHENAAA
SCHEMBL4655566 0.78 ALDH1A1 (0.52) ALDH1A1EPHX1ATMACHENAAA
SCHEMBL722043 0.78 EPHX1 (0.64) EPHX1ACHENAAA
SCHEMBL5491470 0.78 ATM (0.54) ALDH1A1EPHX1ATMACHENAAA
SCHEMBL28306636 0.77 ALDH1A1 (0.56) ALDH1A1EPHX1ATMACHENAAA
SCHEMBL27811468 0.77 ALDH1A1 (0.56) ALDH1A1EPHX1ATMACHENAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090238875-A1 Chitosan or Hyaluronic Acid-Poly(Ethylene Oxide)-and Chitosan-Hyaluronic Acid-Poly(Ethylene Oxide)-Based Hydrogel and Manufacturing Method Therefor SEOUL NATIONAL UNIVERSITY OF TECHNOLOGY CENTER FOR INDUSTRY COLLABORATION (KR) 2009-09-24 US disclosed
WO-2007083870-A1 CHITOSAN OR HYALURONIC ACID-POLY(ETHYLENE OXIDE)- AND CHITOSAN-HYALURONIC ACID-POLY(ETHYLENE OXIDE)-BASED HYDROGEL AND MANUFACTURING METHOD THEREFOR SEOUL NATIONAL UNIVERSITY OF TECHNOLOGY CENTER FOR INDUSTRY COLLABORATION (KR) 2007-07-26 WO disclosed