Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ITGB1 | P05556 | 15/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 10/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829907 | 0.94 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2ITGB1ITGA5ITGA4 | |
| SCHEMBL3837320 | 0.89 | NAMPT (0.50) | ALDH1A1SMN1; SMN2ITGB1ITGA4ITGB7 | |
| SCHEMBL3830610 | 0.88 | ITGA4 (0.51) | ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL3835571 | 0.87 | ITGA4 (0.52) | ITGB1ITGA4ITGB7 | |
| SCHEMBL3831811 | 0.87 | ITGA4 (0.51) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL3821331 | 0.86 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2ITGB1ITGA5ITGA4 | |
| SCHEMBL3830834 | 0.85 | ITGA4 (0.51) | ITGB1ITGA4ITGB7 | |
| SCHEMBL3836819 | 0.85 | ITGA4 (0.48) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL3833939 | 0.85 | ITGA4 (0.47) | ITGB1ITGA5ITGA4ITGB7ITGB3 | |
| SCHEMBL3835954 | 0.85 | ITGA4 (0.47) | ITGB1ITGA5ITGA4ITGB7ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137601-A1 | L-Phenylalanine Derivatives | ASTRAZENECA AB (SE) | 2009-05-28 | — | — | US | claimed |
| US-20090137601-A1 | L-Phenylalanine Derivatives | ASTRAZENECA AB (SE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137601-A1 | L-Phenylalanine Derivatives | ITGB5, ITGB1, ITGA2B | ALDH1A1 1156/4885SMN1; SMN2 2699/4885ITGB1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.