Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13777230 | 0.86 | RAB9A (0.49) | KDM4ERAB9ANPC1MAPTACSS2 | |
| SCHEMBL12082560 | 0.84 | KDM4E (0.51) | KDM4EHSD17B10RAB9ANPC1MAPT | |
| SCHEMBL13313014 | 0.83 | KDM4E (0.57) | KDM4EHSD17B10RAB9ANPC1MAPT | |
| SCHEMBL4159853 | 0.83 | KMT2A (0.49) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL31569891 | 0.81 | RAB9A (0.52) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL103416 | 0.81 | PIK3CD (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1HDAC6 | |
| SCHEMBL10368883 | 0.80 | NLRP3 (0.57) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11955229 | 0.80 | KDM4E (0.48) | KDM4EHSD17B10RAB9ANPC1MAPT | |
| SCHEMBL14736501 | 0.80 | MAPT (0.50) | KDM4EHSD17B10RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL14736580 | 0.79 | KDM4E (0.50) | KDM4EHSD17B10RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283911-A | Preparation method of dabigatran etexilate | 宿迁盛基医药科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116003384-A | Synthesis method of dabigatran etexilate important intermediate | 宿迁盛基医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |
| US-20090192169-A1 | Bicyclic Benzimidazole Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| US-20090192169-A1 | Bicyclic Benzimidazole Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| US-20090192169-A1 | Bicyclic Benzimidazole Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| WO-2007115077-A2 | BICYCLIC BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |
| EP-0012291-A1 | Process for the preparation of benzimidazolyl benzofuranes | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192169-A1 | Bicyclic Benzimidazole Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators | GRM1, GRIN1, GRM2 | KDM4E 3143/4885HSD17B10 3994/4885RAB9A 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.