Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.31 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928928 | 0.85 | ALPL (0.65) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL4008228 | 0.83 | ALPL (0.43) | ALPLKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL646283 | 0.82 | KDM4E (1.00) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL3928703 | 0.78 | ALPL (0.54) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL4305550 | 0.75 | ALPL (0.60) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL4306859 | 0.75 | ALPL (0.57) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL4727174 | 0.72 | ALPL (0.51) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL13539296 | 0.72 | ALPL (0.78) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL28898102 | 0.72 | ALPL (0.78) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL4728616 | 0.71 | ALPL (0.50) | ALPLKDM4EHSD17B10ALDH1A1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010824-A1 | DIHYDROCHROMENOPYRAZOLE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-01-22 | — | — | WO | claimed |