Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.76 |
| ▸ | TACR2 | P21452 | 19/20 | 0.76 |
| ▸ | TAC3 | Q9UHF0 | 6/20 | 0.70 |
| ▸ | TACR3 | P29371 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4149358 | 1.00 | TACR1 (0.76) | TACR1TACR2TAC3TACR3 | |
| SCHEMBL4147327 | 0.94 | TACR1 (0.84) | TACR1TACR2TAC3TACR3 | |
| Trifluoroacetic Acid SCHEMBL4155081 | 0.90 | TACR2 (0.70) | TACR1TACR2TAC3TACR3 | |
| Trifluoroacetic Acid SCHEMBL4155082 | 0.90 | TACR2 (0.70) | TACR1TACR2TAC3TACR3 | |
| Trifluoroacetic Acid SCHEMBL4149844 | 0.89 | TACR1 (0.67) | TACR1TACR2TAC3TACR3 | |
| Trifluoroacetic Acid SCHEMBL4149842 | 0.89 | TACR1 (0.67) | TACR1TACR2TAC3TACR3 | |
| SCHEMBL4153560 | 0.89 | TACR2 (0.84) | TACR1TACR2TAC3TACR3 | |
| Trifluoroacetic Acid SCHEMBL4153185 | 0.88 | TACR2 (0.72) | TACR1TACR2TAC3TACR3 | |
| Trifluoroacetic Acid SCHEMBL4153182 | 0.88 | TACR2 (0.72) | TACR1TACR2TAC3TACR3 | |
| SCHEMBL4140772 | 0.87 | TACR2 (0.83) | TACR1TACR2TAC3TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470816-B2 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-06-18 | — | — | US | disclosed |
| WO-2009072643-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | NTSR2, NTSR1, HNMT | TACR1 9/4885TACR2 19/4885TAC3 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.