Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738967 | 0.84 | CCR1 (0.42) | CCR1CCR5CCR8CYP2A6KMT2A | |
| SCHEMBL24729161 | 0.83 | CCR1 (0.64) | CCR1CCR5CCR8CYP2A6KMT2A | |
| SCHEMBL4151216 | 0.82 | KDM4E (0.43) | CCR1CCR5CCR8KDM4ENOS3 | |
| SCHEMBL18516195 | 0.78 | CCR1 (0.52) | CCR1CCR5CCR8CYP2A6KMT2A | |
| SCHEMBL4159050 | 0.73 | CYP2A6 (0.43) | CYP2A6KDM4ENOS3NOS1NOS2 | |
| SCHEMBL18809327 | 0.71 | CCR1 (0.61) | CCR1CCR5CCR8CYP2A6KMT2A | |
| SCHEMBL26055298 | 0.69 | CCR1 (0.59) | CCR1CCR5CCR8CYP2A6KMT2A | |
| SCHEMBL29481396 | 0.69 | CCR1 (0.65) | CCR1CCR5CCR8CYP2A6KMT2A | |
| SCHEMBL1149763 | 0.69 | CCR1 (0.65) | CCR1CCR5CCR8CYP2A6KMT2A | |
| SCHEMBL29397106 | 0.69 | CCR1 (1.00) | CCR1CCR5CCR8CYP2A6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212048-B2 | Method of producing aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | AHR, CYP1A1, ARNT | CCR1 524/4885CCR5 1735/4885CCR8 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.