SCHEMBL4150952

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4151534	0.85	CASR (0.69)	CASRNR1I2
	SCHEMBL4138506	0.81	CASR (0.78)	CASRNR1I2
	SCHEMBL4144024	0.81	TP53 (0.55)	TP53CASRNR1I2ALDH1A1USP2
	SCHEMBL13851597	0.81	CASR (0.58)	TP53CASRNR1I2ALDH1A1USP2
	SCHEMBL3343132	0.80	CASR (0.57)	CASRNR1I2ALDH1A1USP2CYP1A2
	SCHEMBL3381858	0.80	CASR (0.72)	TP53CASRNR1I2ALDH1A1USP2
	SCHEMBL4152732	0.80	TP53 (0.54)	TP53CASRNR1I2ALDH1A1USP2
	SCHEMBL4140230	0.79	TP53 (0.49)	TP53CASRNR1I2ALDH1A1USP2
	SCHEMBL4141856	0.78	CASR (0.60)	TP53CASRNR1I2ALDH1A1USP2
	SCHEMBL4138510	0.78	CASR (0.67)	TP53CASRNR1I2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.