Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933952 | 0.73 | PTGDR2 (0.58) | — | |
| SCHEMBL14367479 | 0.71 | KMT2A (0.43) | S1PR1S1PR5PTGER1 | |
| SCHEMBL3936575 | 0.68 | KMT2A (0.49) | S1PR1S1PR5 | |
| SCHEMBL3937820 | 0.65 | PTGDR2 (0.58) | — | |
| SCHEMBL3939170 | 0.64 | PTGDR2 (0.61) | — | |
| SCHEMBL1584485 | 0.63 | FFAR1 (1.00) | FFAR1PPARGS1PR1S1PR5LTK | |
| SCHEMBL1604202 | 0.63 | FFAR1 (1.00) | FFAR1PPARGS1PR1S1PR5LTK | |
| SCHEMBL3931978 | 0.61 | MEN1 (0.54) | — | |
| SCHEMBL3937365 | 0.61 | PTGDR2 (0.53) | — | |
| SCHEMBL12708019 | 0.61 | FFAR1 (0.83) | FFAR1PPARGS1PR1S1PR5LTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |