Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151684 | 0.98 | RIPK1 (0.41) | RIPK1ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL10634567 | 0.81 | RIPK1 (0.42) | RIPK1ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL1538376 | 0.81 | RIPK1 (0.42) | RIPK1ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL6741619 | 0.80 | TAAR1 (0.41) | RIPK1ALDH1A1MAPK1TAAR1ADRA2A | |
| SCHEMBL28600445 | 0.77 | CYP2D6 (0.42) | RIPK1ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL14944876 | 0.77 | CYP1A2 (0.42) | RIPK1ALDH1A1MAPK1CACNA1FCHRM2 | |
| SCHEMBL18470550 | 0.77 | TAAR1 (0.50) | RIPK1CYP3A4CACNA1FCHRM2CHRM1 | |
| SCHEMBL416895 | 0.77 | TAAR1 (0.50) | RIPK1CYP3A4CACNA1FCHRM2CHRM1 | |
| SCHEMBL14431333 | 0.77 | TAAR1 (0.50) | RIPK1CYP3A4CACNA1FCHRM2CHRM1 | |
| SCHEMBL3088976 | 0.77 | MAPK1 (0.46) | RIPK1ALDH1A1ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329529-A | Traction fluids for traction drive transmissions | NIPPON OIL CO., LTD. (JP) | 1982-05-11 | — | — | US | claimed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-0176366-B1 | IMPREGNATED CAPACITOR | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-01-25 | — | — | EP | disclosed |
| US-4631632-A | METALLIZED POLYPROPYLENE FILM IMPREGNATED WITH DIELECTRIC HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1986-12-23 | — | — | US | disclosed |