Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13449471 | 0.83 | TDP1 (0.49) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL14744344 | 0.83 | TDP1 (0.44) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL22950318 | 0.81 | TDP1 (0.43) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL1233767 | 0.81 | TDP1 (0.43) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL2562318 | 0.81 | TDP1 (0.46) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL24875278 | 0.81 | MEN1 (0.41) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL26498818 | 0.81 | MAOA (0.53) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL4202727 | 0.80 | TDP1 (0.48) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL12698678 | 0.80 | TDP1 (0.48) | TDP1MEN1KMT2AGAAEPHX1 | |
| SCHEMBL843323 | 0.80 | TDP1 (0.48) | TDP1MEN1KMT2AGAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023860-B2 | Pro-drugs for controlled release of biologically active compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-9023860-B2 | Pro-drugs for controlled release of biologically active compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | 3I, LP | 2009-05-28 | — | — | US | disclosed |
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | 3I, LP | 2009-05-28 | — | — | US | disclosed |
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | 3I, LP | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | CRH, FURIN, PEPD | TDP1 2767/4885MEN1 335/4885KMT2A 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.