SCHEMBL4151935

SCHEMBL4151935

C=CC(=O)Oc1ccc(C(=O)OC(C)(C)C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.51
THRB P10828 2/20 0.49
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PRSS1 P07477 1/20 0.38
ACR P10323 1/20 0.38
KMT2A Q03164 2/20 0.38
GFER P55789 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4143696 0.83 ELANE (0.64) ELANETHRBCA2KMT2AMEN1
SCHEMBL7455238 0.82 HSD17B10 (0.53) THRBMAPTTDP1L3MBTL1PRSS1
SCHEMBL5248937 0.81 THRB (0.54) ELANETHRBCA1CA2CA12
SCHEMBL5984170 0.81 ELANE (0.61) ELANECA1CA2CA12CA9
SCHEMBL4906800 0.81 CA1 (0.60) THRBCA1CA2CA12CA9
SCHEMBL10719776 0.81 MAPT (0.54) ELANETHRBMAPTTDP1L3MBTL1
SCHEMBL109451 0.80 CA1 (0.61) ELANECA1CA2CA12CA9
SCHEMBL20507051 0.79 THRB (0.51) ELANETHRBKMT2AHSD17B10
SCHEMBL9322523 0.79 ELANE (0.54) ELANECA1CA2CA12CA9
SCHEMBL21667243 0.79 ELANE (0.58) ELANECA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130419-A1 FOAM SHEET AND PRODUCTION PROCESS THEREOF OJI PAPER CO., LTD (JP) 2009-05-21 US disclosed
US-20060210785-A1 Foamed product in a sheet form and method for production thereof OJI PAPER CO., LTD. (JP) 2006-09-21 US disclosed
EP-1647570-A1 FOAMED PRODUCT IN A SHEET FORM AND METHOD FOR PRODUCTION THEREOF Oji Paper Co., Ltd. (JP) 2006-04-19 EP disclosed