Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 15/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 14/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 7/20 | 0.45 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13851720 | 0.94 | ITGB1 (0.52) | ITGA4ITGB1ITGB7ITGA2CNR2 | |
| SCHEMBL3823453 | 0.89 | ITGA4 (0.55) | ITGA4ITGB1ITGB7ITGA2ITGA5 | |
| SCHEMBL3824395 | 0.88 | ITGB1 (0.48) | ITGA4ITGB1ITGB7ITGA2ITGA5 | |
| SCHEMBL13851498 | 0.84 | ITGA4 (0.44) | ITGA4ITGB1ITGB7ITGA2ITGA5 | |
| SCHEMBL8242092 | 0.84 | CYP2D6 (0.56) | ITGA4ITGB1ITGB7ITGA5CNR2 | |
| SCHEMBL8245362 | 0.81 | SLC6A9 (0.46) | ITGA4ITGB1ITGB7ITGA2ITGA5 | |
| SCHEMBL13726463 | 0.80 | ATM (0.59) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL5786216 | 0.80 | TSHR (0.57) | ITGA4ITGB1ITGB7ITGA2ITGA5 | |
| SCHEMBL3819618 | 0.80 | TSHR (0.57) | ITGA4ITGB1ITGB7ITGA2ITGA5 | |
| SCHEMBL4928013 | 0.80 | ITGB1 (0.54) | ITGA4ITGB1ITGB7ITGA2ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137601-A1 | L-Phenylalanine Derivatives | ASTRAZENECA AB (SE) | 2009-05-28 | — | — | US | disclosed |
| US-20090137601-A1 | L-Phenylalanine Derivatives | ASTRAZENECA AB (SE) | 2009-05-28 | — | — | US | disclosed |
| US-20090137601-A1 | L-Phenylalanine Derivatives | ASTRAZENECA AB (SE) | 2009-05-28 | — | — | US | disclosed |
| WO-2007060408-A2 | L-PHENYLALANINE DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | ASTRAZENECA AB (SE) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137601-A1 | L-Phenylalanine Derivatives | ITGB5, ITGB1, ITGA2B | ITGA4 23/4885ITGB1 2/4885ITGB7 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.