Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 6/20 | 0.49 |
| ▸ | TACR1 | P25103 | 6/20 | 0.49 |
| ▸ | TAC3 | Q9UHF0 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SPTLC2 | O15270 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153052 | 1.00 | TACR2 (0.49) | TACR2TACR1TAC3LMNATP53 | |
| SCHEMBL4149849 | 0.92 | CHRNA7 (0.48) | TACR2TACR1TAC3SPTLC2TAS1R3 | |
| SCHEMBL4141880 | 0.92 | CHRNA7 (0.48) | TACR2TACR1TAC3SPTLC2TAS1R3 | |
| SCHEMBL4153336 | 0.92 | CHRNA7 (0.48) | TACR2TACR1TAC3SPTLC2TAS1R3 | |
| SCHEMBL4157133 | 0.90 | SSTR3 (0.49) | TACR2TACR1SPTLC2TAS1R3TAS1R2 | |
| SCHEMBL4141183 | 0.90 | TACR2 (0.49) | TACR2TACR1TAC3SPTLC2TAS1R3 | |
| SCHEMBL4141180 | 0.90 | TACR2 (0.49) | TACR2TACR1TAC3SPTLC2TAS1R3 | |
| SCHEMBL4157136 | 0.90 | SSTR3 (0.49) | TACR2TACR1SPTLC2TAS1R3TAS1R2 | |
| SCHEMBL4154140 | 0.89 | SSTR3 (0.52) | TACR2TACR1TAC3SPTLC2TAS1R3 | |
| SCHEMBL4154136 | 0.89 | SSTR3 (0.52) | TACR2TACR1TAC3SPTLC2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470816-B2 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | NTSR2, NTSR1, HNMT | TACR2 19/4885TACR1 9/4885TAC3 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.