Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769421 | 0.85 | HTR2A (0.50) | HTR2ASSTR2SSTR4CYP2A6L3MBTL1 | |
| SCHEMBL27481886 | 0.81 | L3MBTL1 (0.38) | HTR2ASSTR2SSTR4CYP1A2CYP2D6 | |
| SCHEMBL20563318 | 0.79 | TAAR1 (0.50) | TAAR1HTR2AHTR6MPOCYP1A2 | |
| SCHEMBL27542076 | 0.79 | POLB (0.41) | SSTR2SSTR4CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL7247940 | 0.79 | DHODH (0.49) | TAAR1HTR2AHTR6MPOCYP1A2 | |
| SCHEMBL4153655 | 0.78 | TAAR1 (0.47) | TAAR1HTR2AHTR6MPOCYP1A2 | |
| SCHEMBL4339469 | 0.77 | L3MBTL1 (0.41) | HTR2ASSTR2SSTR4CYP1A2CYP2D6 | |
| SCHEMBL28611445 | 0.77 | L3MBTL1 (0.41) | HTR2ASSTR2SSTR4CYP1A2CYP2D6 | |
| SCHEMBL15352016 | 0.77 | L3MBTL1 (0.41) | HTR2ASSTR2SSTR4CYP1A2CYP2A6 | |
| SCHEMBL28948705 | 0.77 | PTGS2 (0.42) | HTR2ACYP1A2CYP2D6CYP2A6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192194-A1 | Cyclic Amine Derivatives, Processes For Their Preparation, And Pharmaceutical Compositions Containing Them | ALVARO GIUSEPPE | 2009-07-30 | — | — | US | disclosed |
| US-20070073061-A1 | Cyclic amine derivatives, processes for their preparation, and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073061-A1 | Cyclic amine derivatives, processes for their preparation, and pharmaceutical compositions containing them | SLC6A4, OPRL1, HCRTR1 | TAAR1 64/4885HTR2A 65/4885SSTR2 166/4885 |
| US-20090192194-A1 | Cyclic Amine Derivatives, Processes For Their Preparation, And Pharmaceutical Compositions Containing Them | SLC6A4, OPRL1, HCRTR1 | TAAR1 64/4885HTR2A 65/4885SSTR2 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.