Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19132780 | 0.86 | ALOX15 (0.53) | ALDH1A1POLBNPSR1L3MBTL1DPP4 | |
| SCHEMBL3963177 | 0.82 | NPSR1 (0.51) | ALDH1A1NPSR1L3MBTL1TSHRUSP2 | |
| SCHEMBL27978853 | 0.82 | L3MBTL1 (0.59) | ALDH1A1NPSR1L3MBTL1TSHRUSP2 | |
| SCHEMBL26666375 | 0.81 | POLB (0.61) | ALDH1A1POLBTSHRALOX15MAPK1 | |
| SCHEMBL1001922 | 0.81 | HPGD (0.62) | ALDH1A1POLBTSHRHPGDNPC1 | |
| SCHEMBL14374144 | 0.81 | HPGD (0.62) | ALDH1A1POLBTSHRHPGDNPC1 | |
| SCHEMBL21166647 | 0.80 | NPSR1 (0.47) | ALDH1A1NPSR1L3MBTL1DPP4DPP9 | |
| SCHEMBL9001768 | 0.80 | POLB (0.62) | ALDH1A1POLBTSHRHPGDNPC1 | |
| SCHEMBL5426553 | 0.79 | HPGD (0.62) | ALDH1A1POLBTSHRHPGDNPC1 | |
| SCHEMBL4359670 | 0.79 | HPGD (0.59) | ALDH1A1POLBTSHRHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |