SCHEMBL4154512

SCHEMBL4154512

CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)[C@H](C(=O)OC(C)(C)C)C(C)C

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 14/20 0.53
LTB4R2 Q9NPC1 5/20 0.51
ABCB11 O95342 1/20 0.51
GP6 Q9HCN6 1/20 0.51
AGT P01019 2/20 0.44
AGTR2 P50052 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8140438 0.94 AGTR1 (0.56) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL29670077 0.92 AGTR1 (0.63) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL2443650 0.92 AGTR1 (0.63) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL1259493 0.92 AGTR1 (0.63) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL2913 0.91 AGTR1 (0.53) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL12894045 0.91 AGTR1 (0.53) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL1891052 0.91 AGTR1 (0.62) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL2828658 0.91 AGTR1 (0.62) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL28455049 0.91 AGTR1 (0.62) AGTR1LTB4R2ABCB11GP6AGT
SCHEMBL13773306 0.90 AGTR1 (0.54) AGTR1LTB4R2ABCB11GP6AGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090124577-A1 Intermediate Compounds for the Preparation of an Angiotensin II Receptor Antagonist ENANTIA SI 2009-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124577-A1 Intermediate Compounds for the Preparation of an Angiotensin II Receptor Antagonist AGTR2, AGTR1, ACE AGTR1 2/4885LTB4R2 704/4885ABCB11 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.