Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | S100B | P04271 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632310 | 0.85 | CYP3A4 (0.56) | CYP3A4TSHRCA2CA12CA9 | |
| SCHEMBL9795262 | 0.81 | CYP3A4 (0.44) | CYP3A4TSHRCA2CA12CA9 | |
| SCHEMBL240228 | 0.80 | CYP3A4 (0.42) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL4916246 | 0.76 | CYP3A4 (0.47) | CYP3A4TSHRCA2CA12CA9 | |
| SCHEMBL4916235 | 0.74 | CYP3A4 (0.45) | CYP3A4TSHRCA2CA12CA9 | |
| SCHEMBL14261700 | 0.74 | CYP3A4 (0.80) | CYP3A4TSHRCA2MAPK1TDP1 | |
| SCHEMBL13873043 | 0.74 | NR1H2 (0.56) | CYP3A4TSHRCA2CA12CA9 | |
| SCHEMBL9795547 | 0.74 | CYP3A4 (0.65) | CYP3A4TSHRCA2CA12CA9 | |
| SCHEMBL9795282 | 0.74 | CYP3A4 (0.38) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL15430 | 0.73 | CYP3A4 (0.70) | CYP3A4TSHRCA2MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1609362-B1 | Non-systemic control of parasites | BAYER IP GMBH (DE) | 2015-03-18 | — | — | EP | disclosed |
| US-8728507-B2 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-20 | — | — | US | disclosed |
| US-7517535-B2 | Non-systemic control of parasites | BAYER ANIMAL HEALTH GMBH (DE) | 2009-04-14 | — | — | US | disclosed |
| US-20080108670-A1 | NON-SYSTEMIC CONTROL OF PARASITES | BAYER HEALTHCARE AG (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080108671-A1 | NON-SYSTEMIC CONTROL OF PARASITES | BAYER HEALTHCARE AG (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20060276517-A1 | Non-systemic control of parasites | BAYER HEALTHCARE AG (DE) | 2006-12-07 | — | — | US | disclosed |
| EP-1609362-A2 | Non-systemic control of parasites | Bayer HealthCare AG (DE) | 2005-12-28 | — | — | EP | disclosed |
| EP-0682869-B1 | Non-systemic control of parasites | BAYER HEALTHCARE AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| US-20050222217-A1 | Non-systemic control of parasites | BAYER HEALTHCARE AG (DE) | 2005-10-06 | — | — | US | disclosed |
| US-6896891-B2 | Non-systemic control of parasites | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-24 | — | — | US | disclosed |
| US-6329374-B1 | CONTROLLING PARASITES SUCH AS LICE AND FLEAS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-11 | — | — | US | disclosed |
| US-20010044456-A1 | Antagonists/agonists of nicotinergic acetylcholine receptors in insects; imidacloprid; such as fleas, lice and flies | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-11-22 | — | — | US | disclosed |
| US-20010041723-A1 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-11-15 | — | — | US | disclosed |
| US-20010027201-A1 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-10-04 | — | — | US | disclosed |
| US-20010021716-A1 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-09-13 | — | — | US | disclosed |
| US-6232328-B1 | CONTACTING FLEAS AND LIC ON A HUMAN OR ANIMALS WITH AN IMIDAZOLINIUM COMPOUND TO KILL FLIES AND INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-0682869-A1 | Non-systemic control of parasites | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| US-5294445-A | Animal collars | BAYER AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| EP-0569791-A2 | Shaped bodies for the control of ektoparasites on animals | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0528303-A1 | Shaped bodies for the control of undesired organisms | BAYER AG (DE) | 1993-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276517-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | CYP3A4 1573/4885TSHR 33/4885CA2 2405/4885 |
| US-20080108671-A1 | NON-SYSTEMIC CONTROL OF PARASITES | CHRNG, CHRNA1, CHRM3 | CYP3A4 1573/4885TSHR 33/4885CA2 2405/4885 |
| US-20010021716-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | CYP3A4 1573/4885TSHR 33/4885CA2 2405/4885 |
| US-20050222217-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | CYP3A4 1573/4885TSHR 33/4885CA2 2405/4885 |
| US-20080108670-A1 | NON-SYSTEMIC CONTROL OF PARASITES | CHRNG, CHRNA1, CHRM3 | CYP3A4 1573/4885TSHR 33/4885CA2 2405/4885 |
| US-20010027201-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | CYP3A4 1573/4885TSHR 33/4885CA2 2405/4885 |
| US-20010044456-A1 | Antagonists/agonists of nicotinergic acetylcholine receptors in insects; imidacloprid; such as fleas, lice and flies | CHRNG, CHRNE, CHRNA1 | CYP3A4 1238/4885TSHR 39/4885CA2 3223/4885 |
| US-20010041723-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | CYP3A4 1573/4885TSHR 33/4885CA2 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.