SCHEMBL9795282

SCHEMBL9795282

O=C=NS(=O)(=O)N=C=O.O=C=Nc1ccc(-c2ccc3cc2-3)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 2/20 0.36
MAPK1 P28482 1/20 0.36
TRPA1 O75762 1/20 0.34
CYP1A2 P05177 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL8589758 0.84 CYP3A4 (0.44) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL14688874 0.75 MAPK1 (0.43) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL9229680 0.75 MAPK1 (0.43) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL9795262 0.74 CYP3A4 (0.44) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL4154543 0.74 CYP3A4 (0.44) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL240228 0.73 CYP3A4 (0.42) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL10866723 0.73 CYP3A4 (0.37) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL28571018 0.71 TDP1 (0.37) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL1046649 0.70 CYP3A4 (0.56) CYP3A4TSHRTDP1MAPK1TRPA1
SCHEMBL9795283 0.70 TDP1 (0.50) CYP3A4TSHRTDP1MAPK1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5045226-A Reaction product of tin compound with sulfonyl isocyanate, storage stability, polyurethanes BAYER AKTIENGESELLSCHAFT (DE) 1991-09-03 US disclosed