Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926630 | 0.85 | CSF1R (0.43) | PTGER1GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL4158329 | 0.80 | PTGER1 (0.42) | PTGER1GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL4154318 | 0.80 | PTGER1 (0.42) | PTGER1GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL4148470 | 0.80 | PTGER1 (0.43) | PTGER1CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL4924658 | 0.78 | CSF1R (0.42) | PTGER1GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL4155131 | 0.78 | PTGER1 (0.54) | PTGER1GABRA2GABRB2CYP2C9MEN1 | |
| SCHEMBL5619619 | 0.78 | PTGER1 (0.45) | PTGER1CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL4918882 | 0.76 | PTGER1 (0.45) | PTGER1CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL4914240 | 0.76 | PTGER1 (0.51) | PTGER1GABRA2GABRB2CYP2C9MEN1 | |
| SCHEMBL4922991 | 0.74 | GABRG2 (0.43) | PTGER1GABRG2GABRB3GABRA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | PTGER1 246/4885GABRG2 2702/4885GABRB3 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.