Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531377 | 0.89 | CETP (0.58) | CETPAKR1C3AKR1C2NR1I2 | |
| SCHEMBL531336 | 0.88 | CETP (0.56) | CETPAKR1C3AKR1C2NR1I2 | |
| SCHEMBL6708110 | 0.83 | CFTR (0.51) | CETPAKR1C3AKR1C2CFTR | |
| SCHEMBL29786763 | 0.82 | CFTR (0.48) | CETPAKR1C3AKR1C2CFTR | |
| SCHEMBL904259 | 0.81 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL904252 | 0.81 | CFTR (0.47) | CETPCFTR | |
| SCHEMBL5165035 | 0.81 | CETP (0.54) | CETPNR1I2 | |
| SCHEMBL29786750 | 0.80 | CETP (0.49) | CETPAKR1C3AKR1C2NR1I2 | |
| SCHEMBL23846705 | 0.80 | CETP (0.53) | CETPNR1I2 | |
| SCHEMBL29786780 | 0.80 | CETP (0.53) | CETPNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041253-A1 | COMPOUNDS FOR INCREASE OF HDL-C LEVEL AND USES THEREOF | ZHEJIANG BETA PHARMA INC. (CN) | 2012-04-05 | — | — | WO | disclosed |