Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.64 |
| ▸ | GPX4 | P36969 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164807 | 0.93 | ALDH1A1 (0.62) | TP53NPC1RAB9APAX8GPX4 | |
| SCHEMBL14229121 | 0.87 | TP53 (0.69) | TP53NPC1RAB9APAX8GPX4 | |
| SCHEMBL4163290 | 0.87 | ALDH1A1 (0.61) | TP53NPC1RAB9APAX8GPX4 | |
| SCHEMBL4154740 | 0.85 | TP53 (0.58) | TP53NPC1RAB9APAX8GPX4 | |
| SCHEMBL4168776 | 0.84 | TP53 (0.66) | TP53NPC1RAB9APAX8ALDH1A1 | |
| SCHEMBL24496384 | 0.81 | ALDH1A1 (0.80) | TP53NPC1RAB9APAX8GPX4 | |
| SCHEMBL4167183 | 0.80 | TP53 (0.64) | TP53NPC1RAB9APAX8GPX4 | |
| SCHEMBL4170594 | 0.79 | NPC1 (0.65) | TP53NPC1RAB9APAX8GPX4 | |
| SCHEMBL4159010 | 0.79 | NPC1 (0.65) | TP53NPC1RAB9APAX8GPX4 | |
| SCHEMBL4161699 | 0.79 | NPC1 (0.65) | TP53NPC1RAB9APAX8GPX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | TP53 1939/4885NPC1 3120/4885RAB9A 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.