Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.58 |
| ▸ | GPX4 | P36969 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164807 | 0.92 | ALDH1A1 (0.62) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL14229121 | 0.88 | TP53 (0.69) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL4154918 | 0.85 | TP53 (0.64) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL4149099 | 0.83 | TP53 (0.62) | TP53NPC1RAB9APAX8MEN1 | |
| SCHEMBL4163295 | 0.83 | TP53 (0.83) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL4163290 | 0.79 | ALDH1A1 (0.61) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL23222221 | 0.78 | ALDH1A1 (0.51) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL4164220 | 0.78 | ALDH1A1 (0.46) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL4155161 | 0.77 | RAB9A (0.56) | TP53ALDH1A1NPC1RAB9APAX8 | |
| SCHEMBL24496384 | 0.75 | ALDH1A1 (0.80) | TP53ALDH1A1NPC1RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | TP53 1939/4885ALDH1A1 2505/4885NPC1 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.